ABIO materials

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Biotech new materials

Production facility with the longest experience in Korea Demonstrating the longest domestic track record of safety /ABIO's unique patented technology

Adipose-Derived Stem Cell Culture Fluid (Raw Material)

  • Use of a differentiated serum-free medium
  • Over 17 years of product manufacturing, demonstrating the longest domestic track record of safety with its production technology
  • The world's first registration of Adipose-Derived Stem Cell Culture Fluid as an International Cosmetic Ingredient (INCI)
    - Trade Name: AAPE
    - INCI Name: Human Adipocyte Conditioned Media Extract.
Adipose-Derived Stem Cell Culture Fluid

A process that induces a large number of growth factors from stem cells (5 stages)

다중 유전자 동시 발현 시스템을 이용한 유효물질 대량생산 포플러 개발

AAPE의 Paracrine Effect

  • Stem cells possess a 'homing effect' ability to locate the damaged areas within the body's organs or tissues. During this process, stem cells secrete various beneficial proteins (cytokines, chemokines, growth factors, angiogenic factors, etc.) and exosomes, inducing regeneration of the damaged area.
  • This beneficial effect brought about by the stem cells releasing useful substances into our body is called the 'Paracrine Effect.'
  • AAPE contains over 150 types of growth factor proteins and exosomesthat enhance the Paracrine Effect.
Cell to cell communication
AAPE®
AAPE®의 유효 성장인자

Adipose-derived Stem Cell Exosomes

ABIO's Stem Cell Exosomes​

  • ABIO's unique serum-free medium and stem cell large-scale cultivation technology are used to mass-produce exosomes.
  • The country's highest and most significant level of exosome product production capacity. 30,000 vials per month.
  • ABIO's stem cell exosomes are outstanding in delivering various beneficial proteins and miRNAs to damaged tissues/cells, thus promoting skin/cell regeneration, conducting immune regulation, and improving hair loss.
ABIO Stem Cell Exosomes

Advanced exosome purification process

Process technology for separating/purifying exosomes at high purity (exosome size, 70~130 nm), high concentration (over 10 billion/mL) from stem cell culture fluid.

Exosome Clusterformation
Precipitation
Dissociation step
Exosome Clusterformation